A man has died after his car left the road and hit a tree.
The 54-year-old was driving south on the A74(M) near to Kirkpatrick Fleming, Dumfries and Galloway, when the crash happened at around 10.10pm on Wednesday.
Police said early reports indicate that there may have been debris on the carriageway near to the scene of the collision.
They are keen to trace a lorry which may have lost timber from its load on Wednesday evening.
Officers are appealing for information about the one-vehicle crash which involved a black-coloured BMW 730 motor car.
Sergeant Bob McNay, of the Lockerbie trunk road patrol group, said: “A full crash scene investigation has been carried out in order to determine the cause of this collision.
“Early reports received indicate that there may have been debris on the carriageway near to the scene of the collision.
“We want to hear from anyone who may have witnessed this collision, or who may have driven on the southbound carriageway near Kirkpatrick Fleming around the time of the collision.
“We also want to identify a southbound vehicle which may have lost a quantity of timber from its load between junctions 19 (Ecclefechan) and 21 (Kirkpatrick Fleming) on Wednesday evening.”