Emergency services are attending an accident that has closed the A68 at Soutra, in Midlothian.
A car and a motorcycle were involved in the collision at around half past seven this morning.
The biker was initially treated by ambulance crews on the scene. He has now been taken to ERI with suspected head injuries and multiple fractures
The Scottish Fire and Rescue Service said no one had to be rescued from the car.
Diversions have been put in place, and accident investigators are expected to start work on the scene.