It's the game in which a Hearts hero can be made and that oppoetunity beckons for Neil Critchley and his players this weekend.
The Leith side are in desperate need of a positive result after last weekend’s dismal collapse to Dundee United at Tannadice. However, they will find their city rivals in fine form with new boss Neil Crithcley having won both of his opening two fixtures.
Over the years, there have been plenty of derby heroes. From the cult heroes to the legends like Rudi Skacel and John Robertson, Hearts have made memories to savour in this fixture over the years.
The Edinburgh Evening News asked on social media for fans' favourite derby moments. Here are 10 of the best...
5. Hibs 0-4 Hearts (02/04/06)
A hat-trick in the 2006 Scottish Cup semi-final was the pinnacle for Hartley in this fixture, having played on both sides. "Obliterated them that day." | SNS Group
6. Hearts 4-4 Hibs (02/01/03)
One of the most memorable derbies of recent times in which Graham Weir struck twice at the death to earn iconic status with Mark de Vries also in on the act alongside Steven Pressley. "By far the greatest ever comeback, the 4-4 at the castle, a late Graham Weir double !! | SNS Group
7. Hearts 2-0 Hibs (30/03/14)
Hibs fans arrived at Tynecastle in jubilant mood with the chance to relegate their neighbours, but the young Hearts side rallied to claim a memorable win. Not bad for a group of "academy boys." | SNS Group
8. Hibs 1-2 Hearts (01/05/10)
The David Obua derby. Scored late, sealed the win, signed off with an unforgettable post-match quip. "That's Gangsta" | SNS Group