Edinburgh-born Weir was diagnosed with motor neurone disease in December 2016.
The former Scotland international, who won 61 caps, used his profile to push for better research to be carried out into MND and appealed for improved care to be given to those afflicted by it.
Here, we take a pictorial look back over his life, his career and his fund-raising work for research into motor neurone disease.
5. MNDF Scotland Golf Day
Doddie Weir with players and friends at the MNDF Scotland Golf Day in July 2022. The annual event raised more than £20,000 for motor neuron disease (MND). Photo: My Name'5 Doddie Foundation Photo: My Name'5 Doddie Foundation
6. Number 5
A photo issued by My Name'5 Doddie Foundation of Doddie Weir's tartan Scotland shirt. Photo: My Name'5 Doddie Foundation
7. Old pals
Former Scotland rugby union stars Doddie Weir and Gregor Townsend. Photo: My Name'5 Doddie Foundation
8. Autumn International
Former Scotland player Doddie Weir with Jamie Ritchie ahead of the Autumn International match at BT Murrayfield Stadium, Edinburgh, on Sunday November 13, 2022. Photo: Jane Barlow